Ruud van Nistelrooy returns to Old Trafford with Leicester City, who were due to play against former Manchester United in the fourth round of the FA Cup.
The Dutchman won the FA Cup with United in 2004, while briefly serving as interim boss of the Red Devils following the departure of Erik ten Hag earlier this season, before taking over the Foxes.
Ruben Amorim's United started their title defense with a dramatic victory over Arsenal on penalties at the Emirates Stadium on Sunday, despite playing with 10 men for more than an hour after Diogo Dalot's red card.
Elsewhere, Championship club Plymouth Argyle's reward for stunning Brentford in the third round is a home match against Premier League leaders Liverpool.
The draw for the fourth round of #EmiratesFACup has been completed
— Emirates FA Cup (@EmiratesFACup) January 12, 2025
Manchester City have won an away match against Leyton Orient of Derby County, while in-form Nottingham Forest and Newcastle United travel to Exeter City and Birmingham City respectively.
After a pair of high-profile games in the Premier League, Aston Villa welcomes Tottenham and Brighton hosts Chelsea, while Everton and Bournemouth also face off.
Ipswich Town and Wolves travel to Championship opposition in Coventry City and Blackburn Rovers, with Fulham getting an away match against Mansfield Town or Wigan Athletic.
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