The reward of Plymouth for the Knock -Out Liverpool is a trip to Premier League champions Manchester City in the FA Cup Fifth round, while holders Manchester United Fulham will play.
Plymouth, which is at the bottom of the Sky BET championship, achieved a famous win of the fourth round against Premier League leaders Liverpool during the weekend.
They are now confronted with a journey to City, after Pep Guardiola had afraid to overcome a first half to beat Leyton Orient 2-1.
Man Utd was pulled at home to Fulham. United beat Leicester 2-1 in controversial circumstances, with Harry Maguire seeming to be in an offside position while he was on his way in the winner of Friday in Old Trafford.
There was no VAR in operation during the fourth round tires at the weekend, but the technology will come into play from the next round.
After having won 2-0 in Everton on Saturday, Bournemouth is confronted with more Premier League opposition with Wolves in the Vitality Stadium.
Brighton, who came from behind to beat Chelsea 2-1, also has a tough assignment because they are gone to Carabao Cup finalists Newcastle.
Cardiff, who needed fines to get past Stoke, is gone to Aston Villa-who hung 2-1 with 2-1 on Sunday.
Crystal Palace will be at home at the Rivals Millwall in Zuid-Londen after having defeated Doncaster 2-0 on Monday, while the winners of Tuesday's draw between Exeter and Nottingham Forest are at home at Ipswich.
There will also be a bond with all the champion ships in the northwest with Preston because of host Burnley.
FA Cup Fifth-Round tires are played around the first weekend of March, with the football club to confirm the full schedule in due course.
Fa Cup fifth round is full
Tires to be played around the first weekend of March
Preston vs Burnley
Aston Villa vs Cardiff City
Crystal Palace vs Millwall
Manchester United vs Fulham
Newcastle vs Brighton
Bournemouth vs Wolves
Manchester City vs Plymouth Argyle
Exeter City/Nottingham Forest vs Ippswich
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