Crystal Palace will host Liverpool at Selhurst Park on Saturday, Palace 12 in the table with 26 points, while Liverpool is in eighth place with 35 points.
One of the biggest matches of Spanish football takes place this week as the Madrid derby sees Real Madrid and Atletico Madrid face off in the Spanish capital.
Arsenal managed to end their winless run in dramatic fashion last time out and regain the top spot in the league table with a record of 17 wins, three defeats and three draws, leaving them on 54 points.
Premier League giants Manchester City will return to the Champions League with an away match in Germany, against RB Leipzig in the round of 16 of the competition on Wednesday.
Liverpool will face Real Madrid in a repeat of the 2021/22 Champions League final, this time they will meet in the round of sixteen after Liverpool finished second in their group and Real Madrid won them both.
Manchester United came off a positive outing in the Europa League knockout game against Barcelona and will be targeting victory upon their return to league action.